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Staff/Senior Staff Scientist Sample Prep

Pacific Biosciences

Menlo Park, CA 94025
  • Biotechnology / Science
  • Healthcare
  • Engineering
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Job Details

Pacific Biosciences of California, Inc (NASDAQ: PACB) is helping scientists forge a better understanding of biology by providing a unique long-read sequencing technology that generates more complete and accurate data, giving them more insights. Our sequencing systems allow scientists to characterize genomes, transcriptomes, and epigenomes from any organism. Scientists use our technology in areas such as human biomedical research, plant and animal sciences, and microbiology and infectious disease studies. Become part of the new paradigm in long-read sequencing and help shape the future of genomic study by joining the PacBio team.


Pacific Biosciences seeks a Staff/Senior Staff Scientist with a strong biochemistry and molecular biology background to join the sample prep team.  This position will contribute to development of the up-front DNA preparation for Pacific Biosciences SMRT sequencing platform, as well as support of internal research efforts, by working with a team that is tasked with continuing innovation of the sample prep component of Pacific Biosciences single molecule real time DNA sequencing system.   The candidate will be working in a fast-paced environment, interacting with scientists and engineers with diverse backgrounds.


Key responsibilities include:

  • Hands-on laboratory work preparing samples and running the PacBio instruments.

  • Analysis, interpretation, and troubleshooting of experimental results.

  • Innovation to improve the Pacific Biosciences SMRT sequencing sample preparation method.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.


  • Ph.D degree in Biochemistry, Molecular Biology or related scientific field.  

  • 2 to 7 years of biochemistry and/or molecular biology laboratory research experience.

  • Technical proficiency in general laboratory practices, particularly biochemistry/molecular biology.

  • NGS template preparation and innovation highly desired.

  • Excellent record-keeping and careful attention-to-detail.

  • Strong presentation and communication skills.

  • Outstanding organizational and interpersonal skills.

  • Enjoy working closely with others as a member of an interdisciplinary team.

  • Prior experience in the biotechnology industry is a plus.

  • Prior hands-on experience in operating next-generation DNA sequencing instruments and assays are a plus.

  • Expertise in DNA modifying enzymes.

  • Quantitative analysis of experimental data.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.
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